Author: multimulti

Chirality 101: Nature’s Left-Right Divide Chirality describes objects that cannot be superimposed on their mirror image, like hands. In fluids, chiral particles (e.g., helical bacteria or engineered microstructures) interact uniquely with swirling flows. Unlike symmetric objects, their handedness dictates whether they drift inward or outward in a vortex . Vortex Flows: More Than Just Whirlpools…

History: How Gel Microchips Emerged from the Cold War The story begins with Dr. Andrei Mirzabekov at Russia’s Center of Biological Microchips. His team sought a way to analyze DNA faster and cheaper during the Human Genome Project. Key milestones: 1988–1997: Early prototypes used polyacrylamide gel to immobilize DNA probes. Probes were unevenly distributed, limiting…

What Is Cellular Computation? Cellular computation leverages biological systems—such as proteins, DNA, or entire cells—to perform logic-based operations. Unlike silicon chips, biological systems excel at parallel processing, adaptability, and energy efficiency. Key approaches include: Genetic Circuits: Engineered DNA that functions like electronic circuits . Neural Networks: Living neurons processing information in real time . Metabolic…

Core Themes: Innovation, Collaboration, and Ethics The Future of Science revolves around three pillars: Innovation Through Interdisciplinarity: Carter argues that breakthroughs like CRISPR and AI-driven drug discovery stem from merging traditionally siloed fields . Collaborative Models: Case studies highlight open-source platforms and global partnerships accelerating vaccine development during the COVID-19 pandemic . Ethical Imperatives: The…

What Makes Electron Crystallography Unique? Electron crystallography leverages the wave-like properties of electrons to probe matter. Key advantages include: Nanoscale Samples: Analyzes crystals as small as 100 nm³, bypassing the need for large, pure crystals . Diverse Applications: From zeolites in catalysis to amyloid fibrils in neurodegenerative diseases . Hybrid Approaches: Combines with cryo-EM or…

Cutting-Edge Innovations in Sample Preparation Sample preparation is the critical first step in proteomics, determining the success of downstream analysis. Key challenges include minimizing protein loss, handling minute quantities (e.g., single cells), and ensuring reproducibility. Solid-Phase Enhancements (SP3/SP4): Single-pot, solid-phase-enhanced methods like SP3 use magnetic beads to capture proteins, enabling rapid, lossless processing. SP4, a…