Research Articles
Single-Cell Foundation Models: A Comprehensive Review of Concepts, Applications, and Future Directions in Biomedical Research
This review provides a comprehensive examination of single-cell foundation models (scFMs), large-scale AI systems pretrained on massive single-cell datasets that are revolutionizing cellular biology and drug discovery.
Tokenization Strategies for Single-Cell Data: From Foundation Models to Clinical Applications
This article provides a comprehensive overview of tokenization strategies that enable artificial intelligence to interpret single-cell genomic data.
Emergent Abilities in Single-Cell Foundation Models: A Comprehensive Guide for Biomedical Researchers
Single-cell foundation models (scFMs) represent a paradigm shift in computational biology, leveraging large-scale pretraining on millions of cells to develop emergent capabilities for downstream biological tasks.
How Single-Cell Foundation Models Work: A Guide for Biomedical Researchers
Single-cell foundation models (scFMs) are transformative AI tools trained on millions of single-cell datasets to decipher the complex language of cellular biology.
Harnessing Self-Supervised Learning for scRNA-seq Data: From Foundational Models to Clinical Translation
Self-supervised learning (SSL) is revolutionizing the analysis of single-cell RNA sequencing (scRNA-seq) data by enabling the extraction of meaningful biological representations from vast, unlabeled datasets.
Transformer Architecture in Single-Cell Biology: A Comprehensive Guide to Foundation Models, Applications, and Benchmarking
The integration of transformer architectures into single-cell biology is revolutionizing how we interpret complex cellular systems.
STR Profiling vs Isoenzyme Analysis: A Modern Guide to Cell Line Authentication
This article provides a comprehensive comparison of Short Tandem Repeat (STR) profiling and isoenzyme analysis for cell line authentication, essential for researchers, scientists, and drug development professionals.
Ethanol vs. Bleach: A Comprehensive Efficacy Comparison for Biomedical Disinfection
This article provides a systematic review for researchers and drug development professionals on the comparative efficacy of ethanol and sodium hypochlorite (bleach) as surface disinfectants.
Single-Use vs. Reusable Systems: A Comprehensive Contamination Risk Assessment for Biopharmaceuticals
This article provides a systematic comparison of contamination risks associated with single-use and reusable systems in biopharmaceutical manufacturing and clinical settings.
Validating Sterilization Protocols for Cell Culture: A Comprehensive Guide for Robust Research and Bioprocessing
This article provides a systematic framework for researchers, scientists, and drug development professionals to validate and optimize sterilization protocols in cell culture systems.